Directions Drink extra water while you are taking this medication to keep from getting dehydrated. It may take up to 48 hours of taking loperamide before your symptoms improve. For best results, keep using the medication as directed. Talk with your doctor if your symptoms do not improve after 10 days of treatment. Loperamide can cause side effects that may impair your thinking or reactions. Be careful if you drive or do anything that requires you to be awake and alert.
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